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Chronic eosinophilic pneumonia: a paediatric case
Davide Tassinari1, Chiara Di Silverio Carulli, Francesca Visciotti
1Department of Paediatric Emergency, S Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. davide.tassinari@aosp.bo.it
Insights
Chronic eosinophilic pneumonia (CEP) is a rare pediatric lung disorder. Prompt diagnosis and corticosteroid treatment led to a dramatic recovery in an 11-year-old asthmatic girl.
Area of Science:
- Pediatric Pulmonology
- Rare Respiratory Diseases
Background:
- Chronic eosinophilic pneumonia (CEP) is a rare inflammatory lung condition affecting children.
- CEP presents with respiratory and systemic symptoms, but generally has a good prognosis.
Observation:
- An 11-year-old girl with asthma presented with a 3-month history of cough, dyspnea, weight loss, and fatigue.
- Imaging revealed peripheral pulmonary infiltrates, nodules with ground-glass halos, and blood eosinophilia, suggesting eosinophilic lung disease (ELD).
Findings:
- Diagnosis of CEP was confirmed after excluding other ELDs.
- The patient showed a dramatic positive response to oral corticosteroid therapy.
Implications:
- Early diagnosis and treatment of pediatric CEP are crucial for favorable outcomes.
- Corticosteroids are effective in managing CEP, even in children with pre-existing asthma.
Abstract:
Chronic eosinophilic pneumonia (CEP) is a rare disorder in children, characterised by respiratory and systemic symptoms, with a generally good prognosis. A 11-year-old asthmatic girl was admitted to our clinic with a 3-month history of progressive cough, dyspnoea, weight loss and asthenia. Peripheral blood eosinophilia, multiple bilateral pulmonary infiltrates to the x-ray, multiple nodules with a surrounding ground-glass halo and peripheral predominance to the chest CT suggested the diagnosis of eosinophilic lung disease (ELD). Further investigations ruled out other ELD and supported diagnosis of CEP. The response to oral corticosteroids was dramatic, no relapses were reported in 2-year follow-up while the patient was under inhaled corticosteroids for pre-existing asthma.
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