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Updated: May 11, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Three-dimensional foveal shape changes after asymptomatic macular posterior vitreous detachment
Kazuyuki Kumagai1, Masanori Hangai, Mariko Furukawa
1Department of Ophthalmology, Kamiiida First General Hospital, Nagoya, Japan.
Purpose:
To show a case in which the shape of the fovea changed after an asymptomatic macular posterior vitreous detachment (PVD).
Methods:
The foveal shape was determined from the spectral-domain optical coherence tomography (OCT) images before and after a spontaneous macular PVD.
Results:
A 66-year-old man with a unilateral macular hole in the right eye presented with a perifoveal PVD in the asymptomatic left eye. One year later, the left eye developed a macular PVD, and OCT measurements showed a 16.7% decrease in the central foveal thickness, and increases in the pit depth by 20.5%, foveola diameter by 14.7%, and pit volume by 19.4%. The thicknesses of the macular subfields of the Early Treatment Diabetic Retinopathy Study were decreased by 13.0% in the central subfield and by 1.4%-6.6% in the other subfields.
Conclusion:
The deepening and widening of the fovea after a macular PVD indicate that a PVD can alter the shape of the fovea.
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