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Detection of Human Leukocyte Antigen Biomarkers in Breast Cancer Utilizing Label-free Biosensor Technology
Published on: March 24, 2015
Breast cancer recognition using a novel hybrid intelligent method
Jalil Addeh1, Ata Ebrahimzadeh
1Department of Electrical and Computer Engineering, Babol University of Technology, Babol, Iran.
Abstract:
Breast cancer is the second largest cause of cancer deaths among women. At the same time, it is also among the most curable cancer types if it can be diagnosed early. This paper presents a novel hybrid intelligent method for recognition of breast cancer tumors. The proposed method includes three main modules: the feature extraction module, the classifier module, and the optimization module. In the feature extraction module, fuzzy features are proposed as the efficient characteristic of the patterns. In the classifier module, because of the promising generalization capability of support vector machines (SVM), a SVM-based classifier is proposed. In support vector machine training, the hyperparameters have very important roles for its recognition accuracy. Therefore, in the optimization module, the bees algorithm (BA) is proposed for selecting appropriate parameters of the classifier. The proposed system is tested on Wisconsin Breast Cancer database and simulation results show that the recommended system has a high accuracy.
