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The effects of periodontal treatment on pregnancy outcomes
Bryan S Michalowicz1, Anders Gustafsson, Vivek Thumbigere-Math
1Department of Developmental and Surgical Sciences, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA. micha002@umn.edu
Insights
Periodontal therapy, including scaling and root planing, does not improve birth outcomes for pregnant women with periodontitis. Research indicates no significant effect on reducing preterm birth or low birthweight rates.
Area of Science:
- Obstetrics and Gynecology
- Periodontology
- Neonatal Health
Background:
- Preterm infants face higher risks for developmental disorders, with increased mortality as gestational age decreases.
- Observational studies suggest a link between poor periodontal health and preterm birth or low birthweight.
- Periodontitis is considered a potentially modifiable risk factor for prematurity.
Purpose of the Study:
- To identify and discuss randomized controlled trials (RCTs) published between January 2011 and July 2012.
- To evaluate whether periodontal therapy impacts rates of preterm birth and low birthweight.
Main Methods:
- Searched major databases: PubMed, ISI Web of Science, and Cochrane Library.
- Identified and analyzed relevant randomized controlled trials (RCTs).
Main Results:
- A single identified RCT showed no significant effect of periodontal treatment on birth outcomes.
- The largest, high-quality trials with low risk of bias consistently indicated no alteration in adverse pregnancy outcomes.
Conclusions:
- Non-surgical periodontal therapy, specifically scaling and root planing, does not enhance birth outcomes in pregnant women diagnosed with periodontitis.
- Current evidence from RCTs does not support periodontal treatment as a method to improve pregnancy outcomes related to preterm birth or low birthweight.
Background:
Preterm infants are at greater risk than term infants for physical and developmental disorders. Morbidity and mortality increases as gestational age at delivery decreases. Observational studies indicate an association between poor periodontal health and risk for preterm birth or low birthweight, making periodontitis a potentially modifiable risk factor for prematurity.
Aim:
To identify randomized controlled trials (RCTs) published between January 2011 and July 2012 and discuss all published RCTs testing whether periodontal therapy reduces rates of preterm birth and low birthweight.
Methods:
Search of databases including PubMed, ISI Web of Science and Cochrane Library.
Results:
The single RCT identified showed no significant effect of periodontal treatment on birth outcomes.
Discussion:
All published trials included non-surgical periodontal therapy; only two included systemic antimicrobials as part of test therapy. The trials varied substantially in terms of sample size, obstetric histories of subjects, study preterm birth rates and the periodontal treatment response. The largest trials - also judged to be high-quality and at low risk of bias - have yielded consistent results, and indicate that treatment does not alter rates of adverse pregnancy outcomes.
Conclusion:
Non-surgical periodontal therapy, scaling and root planing, does not improve birth outcomes in pregnant women with periodontitis.
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