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Updated: May 11, 2026
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011
Clinical features and in-vivo confocal microscopic imaging of fleck corneal dystrophy
Ertuğrul Can1, Emrah Kan, Halil İbrahim Akgün
1Ondokuz Mayıs University, School of Medicine, Department of Ophthalmology, Samsun, Turkey. ertugrulcan73@hotmail.com
Purpose:
To evaluate the value of in-vivo confocal microscopy (CM) in the diagnosis of Fleck corneal dystrophy.
Methods:
Case report and literature review. After complete eye examination of the patient, in-vivo CM was performed. The morphologies of the corneal layers were evaluated by in-vivo CM.
Results:
Slit-lamp examination revealed bilateral gray-white, oval or round discrete opacities in the stroma. Confocal microscopy showed hyper-reflective opacities in enlarged and unremarkable keratocyte nuclei throughout the stroma. The surface epithelium, subbasal nerves, and endothelium showed normal morphology.
Conclusion:
The diagnosis of rare corneal dystrophies such as Fleck corneal dystrophy should sometimes be made only after performing in-vivo confocal microscopy.
