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Related Experiment Video

Updated: May 11, 2026

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08:42

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Published on: May 5, 2015

Baboon-like syndrome in children.

Iria Neri1, Arianna Dondi, Lorenza Ricci

  • 1Department of Specialistic, Diagnostic and Experimental Medicine, Dermatology Unit, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Pediatric Dermatology
|May 1, 2013
PubMed
Summary

Baboon syndrome, a rash on flexural areas and thighs, can be triggered by infections. This is the first reported case of baboon syndrome in a child caused by Epstein-Barr virus and cytomegalovirus coinfection.

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Area of Science:

  • Pediatric Infectious Diseases
  • Dermatology
  • Virology

Background:

  • Baboon syndrome is characterized by specific erythema patterns in flexural areas and thighs.
  • Infectious agents are recognized as potential triggers for baboon syndrome.
  • The etiology of baboon syndrome, particularly in pediatric cases, requires further elucidation.

Observation:

  • A pediatric case presenting with the distinct clinical features of baboon syndrome was observed.
  • The patient exhibited diffuse symmetrical erythema in major flexural areas and V-shaped erythema on the upper anteromedial thighs.
  • Diagnostic investigations revealed a coinfection with Epstein-Barr virus and cytomegalovirus.

Findings:

  • This study reports the first instance of baboon syndrome in a child associated with Epstein-Barr virus and cytomegalovirus coinfection.
  • The findings suggest that viral coinfections can act as a trigger for baboon syndrome in pediatric populations.
  • The specific interplay between these viruses and the dermatological manifestation is highlighted.

Implications:

  • This case expands the known spectrum of triggers for baboon syndrome.
  • It underscores the importance of considering viral etiologies, including coinfections, in pediatric patients presenting with baboon syndrome.
  • Further research is warranted to understand the pathomechanisms linking viral coinfections to baboon syndrome.