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Software for symptom association analysis in pediatric gastroesophageal reflux disease

Alejandro Barriga-Rivera1, Mar Elena, Maria Jose Moya

  • 1Children's Hospital Virgen del Rocío, Seville, Spain.

Computer Methods and Programs in Biomedicine
|May 1, 2013
PubMed

Insights

A new open-source software tool analyzes gastroesophageal reflux (GER) and cardiorespiratory events in children. This tool aids in diagnosing GER disease by assessing symptom association, potentially reducing misdiagnoses and inappropriate treatments.

Area of Science:

  • Pediatric Gastroenterology
  • Medical Informatics
  • Cardiology

Background:

  • Gastroesophageal reflux (GER) disease can cause serious cardiorespiratory symptoms in pediatric patients.
  • Diagnosing GER requires synchronized 24-h esophageal and cardiorespiratory monitoring.
  • Current diagnostic methods lack dedicated computer tools for symptom association analysis.

Purpose of the Study:

  • To present an open-source computer program for analyzing symptom association between GER and cardiorespiratory events.
  • To provide a flexible and accessible tool for researchers and physicians.
  • To facilitate early and accurate diagnosis of GER-related cardiorespiratory symptoms.

Main Methods:

  • Development of an open-source software program.
  • Implementation of synchronized esophageal and cardiorespiratory monitoring data analysis.
  • Inclusion of key metrics: symptom index, symptom sensitivity index, and symptom association probability.

Main Results:

  • The software allows convenient visualization of biological signals.
  • It implements three main metrics for quantifying symptom association.
  • Provides a flexible solution for assessing temporal links between GER and cardiorespiratory episodes.

Conclusions:

  • The developed software facilitates the assessment of GER and cardiorespiratory symptom association in pediatric patients.
  • This tool can help reduce inappropriate medical and surgical treatments.
  • Enables earlier diagnosis of GER disease and associated complications.

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