Related Experiment Video
Updated: May 11, 2026

06:58
Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
Published on: August 17, 2017
[Fall risk and fracture. Aging and fall/fracture].
1Department of Geriatric Medicine, Kyorin University School of Medicine, Japan.
Summary
Falls significantly impact elderly quality of life and daily activities, often stemming from multiple modifiable factors. Interventions like Tai-Chi, medication review, and vitamin D can help prevent falls in older adults.
Area of Science:
- Gerontology
- Public Health
- Geriatric Medicine
Background:
- Falls are a major cause of morbidity and mortality in the elderly, leading to decreased quality of life (QOL) and activities of daily living (ADL).
- Identifying fall causes is complex due to multifactorial origins, with osteoporosis, osteoarthritis, hypnotic medications, and environmental factors being significant and modifiable contributors.
- Hip and vertebral fractures are common consequences of falls in older adults, further exacerbating health decline.
Purpose of the Study:
- To review and synthesize evidence on the causes, assessment, and prevention of falls in community-dwelling elderly individuals.
- To highlight modifiable risk factors and effective interventions for fall prevention in the geriatric population.
Main Methods:
- Review of existing literature, including a Cochrane systematic review from 2009.
- Evaluation of common fall risk assessment tools such as grasping power, one-leg standing time, Timed Up&Go test, and the 22-item fall risk index self-assessment test.
- Identification of interventions supported by evidence for fall prevention.
Main Results:
- The 22-item fall risk index self-assessment test is identified as an easy and effective tool for predicting future falls.
- Grasping power, one-leg standing time, and the Timed Up&Go test are useful in evaluating fall risks.
- Evidence supports exercise (e.g., Tai-Chi), withdrawal of hypnotic drugs, and vitamin D supplementation as effective fall prevention strategies for community-dwelling elderly.
Conclusions:
- Falls in the elderly are multifactorial, necessitating a comprehensive approach to risk assessment and management.
- Modifiable factors like medication, environmental hazards, and underlying health conditions play a crucial role in fall etiology.
- Evidence-based interventions, including exercise, medication review, and nutritional support, are vital for preventing falls and improving the health outcomes of older adults.
Related Concept Videos
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
The Effect of Aging on Tissues
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Aging
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

