Related Experiment Video
Updated: May 11, 2026
10:28
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
[Parkinson's disease: psychological and behavioral disorders]
Daniel Delgadillo-Iniguez1, Jean-Christophe Corvol, Marie-Christine Gély-Nargeot
1Fédération des maladies du système nerveux, AP-HP, Hôpital de la Salpêtrière, Université Pierre et Marie Curie Paris VI.
Psychologie & Neuropsychiatrie Du Vieillissement
|May 2, 2013
Summary
Parkinson's disease patients frequently experience non-motor symptoms like anxiety and depression, which are often overlooked. Improved recognition and diagnosis of these behavioral symptoms are crucial for better patient care and timely interventions.
Area of Science:
- Neurology
- Psychiatry
Context:
- Parkinson's disease (PD) is a neurodegenerative disorder.
- Non-motor symptoms (NMS) are prevalent in PD patients.
Purpose:
- To highlight the underrecognition of NMS in Parkinson's disease.
- To emphasize the impact of NMS on functional abilities.
- To advocate for improved diagnostic approaches.
Summary:
- Patients with Parkinson's disease (PD) commonly exhibit significant anxiety, depression, apathy, fatigue, and sleep disturbances.
- These non-motor symptoms are frequently missed in clinical practice, impacting patients' functional abilities.
- Increased awareness is needed for accurate diagnosis and timely treatment.
Impact:
- Enhanced recognition of NMS can lead to improved patient management.
- Timely therapeutic interventions can mitigate the negative effects of NMS.
- This underscores the importance of a holistic approach to Parkinson's care.
Related Concept Videos
01:15Parkinson's Disease: Overview
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is to...
01:24Parkinson Disease l: Introduction
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
01:24Parkinson's Disease: Treatment
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
01:24Parkinson Disease ll: Pathophysiology
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
01:22Personality Disorders: Paranoid and Schizoid
Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
Paranoid Personality Disorder
Paranoid personality disorder is...
01:19Introduction to Psychological Disorders
Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...