Related Experiment Video
Updated: May 11, 2026

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents
Published on: November 1, 2019
[Nutritional environment in utero and development of obesity]
Hideoki Fukuoka1, Shinji Mukai, Takanori Taniguchi
1Waseda University Comprehensive Research Organization.
Abstract:
Obesity and metabolic syndrome have been acutely increasing worldwide with far-reaching health care and economic implications. The steep increase of these diseases' patients suggests us that environmental and life-style influences, rather than genetic causes, are fueling the epidemic. The developmental origins of health and disease (DOHaD) hypothesis has highlighted the relation between the poor nutritional state of the periconceptional, embryonic, fetal, and early infant phases and the subsequent metabolic disorders in later life. Especially newly constructed epigenetic modification has persisted for long time and induces metabolic disruption. Some experimental animal studies are disclosing developmental programming for diseases are reversible by nutritional or targeted therapeutic interventions during the time of developmental plasticity.
Related Concept Videos
Obesity
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Regulation of Food Intake
Development of the Oral Microbiota
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Bulimia Nervosa

