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Related Experiment Video

Updated: May 11, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

A cholestatic diagnostic dilemma.

Lukas Kalinke¹, Mohammed Rashid

¹Department of Acute Medicine, Princess Royal Hospital, Haywards Heath, UK. lkalinke@gmail.com

BMJ Case Reports

|May 2, 2013

Summary

Hereditary spherocytosis can cause jaundice due to gallstones. This case highlights diagnostic challenges in cholestasis, considering both common and rare intrahepatic causes.

Area of Science:

Hepatology
Gastroenterology
Medical Diagnostics

Background:

Hereditary spherocytosis is a genetic hemolytic anemia.
Jaundice and cholestasis can arise from various causes, including gallstones and intrahepatic pathologies.

Observation:

A 28-year-old man with hereditary spherocytosis presented with severe conjugated hyperbilirubinemia, elevated liver enzymes, and abdominal pain.
Initial investigations revealed gallstones but no biliary dilation, complicating the diagnosis of cholestasis.

Findings:

Subsequent presentation showed choledocholithiasis (gallstones in the bile duct), treated with ERCP and cholecystectomy.
The case underscores the diagnostic complexities of jaundice when atypical presentations and comorbidities are present.

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Last Updated: May 11, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

Implications:

This case emphasizes the importance of a thorough diagnostic approach to jaundice, considering both common posthepatic causes and rarer intrahepatic conditions like benign recurrent intrahepatic cholestasis (BRIC).
It serves as an educational example for clinicians managing patients with unclear cholestasis and underlying hematological disorders.