Metabolic and hormonal consequences of two different meals after a moderate intensity exercise bout in obese

C Maffeis1, R Bonadonna, M Maschio

  • 1Department of Life and Reproduction Sciences, University of Verona, Verona, Italy. claudio.maffeis@univr.it

Insights

A high-fat/low-carbohydrate meal negatively impacts nutrient balance and energy metabolism post-exercise compared to a low-fat/high-carbohydrate meal in obese children.

Area of Science:

  • Pediatric Obesity Research
  • Nutritional Science
  • Exercise Physiology

Background:

  • Understanding postprandial metabolic responses is crucial for managing pediatric obesity.
  • Exercise influences nutrient utilization and hormonal regulation.

Purpose of the Study:

  • To compare the effects of high-fat/low-carbohydrate versus low-fat/high-carbohydrate meals on nutrient balance, hormones, and appetite in prepubertal obese children after exercise.
  • To investigate the relationship between postprandial nutrient balance, satiety, and hormone changes.

Main Methods:

  • Cross-over study with 10 prepubertal obese children.
  • Isocaloric meals (low-fat/high-carb vs. high-fat/low-carb) consumed after 30-min moderate-intensity exercise.
  • Measured substrate oxidation, biochemical parameters, gastrointestinal hormones, and appetite for 5 hours post-meal.

Main Results:

  • The high-fat/low-carb meal resulted in a higher fat balance and lower carbohydrate balance.
  • Elevated energy balance and plasma triglyceride concentrations were observed after the high-fat/low-carb meal.
  • Significantly higher serum glucagon-like peptide-1 concentrations were noted post high-fat/low-carb meal.

Conclusions:

  • A high-fat/low-carbohydrate meal has a less favorable metabolic impact compared to an isoenergetic, isoproteic low-fat/high-carbohydrate meal after exercise.
  • Dietary fat content significantly influences postprandial metabolism and hormonal responses in obese children.
Abstract

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