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Updated: Jan 19, 2026

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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Function of oncogenes in cancer development: a changing paradigm

Carolina Vicente-Dueñas1, Isabel Romero-Camarero, Cesar Cobaleda

  • 1Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/ Universidad de Salamanca, Campus M. de Unamuno s/n, Salamanca, Spain.

The EMBO Journal
|May 2, 2013
PubMed
Summary

Tumour oncogenes reprogram epigenomes, initiating cancer through stem cell changes, not just proliferation. This reveals a new role for oncogenes in cancer origin and suggests novel therapeutic targets.

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