Determining immunisation status of children from history: a diagnostic accuracy study
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Laura Nohavicka1, Helen F Ashdown, Dominic F Kelly
1Department of Paediatrics, University of Oxford, Oxford, UK.
Insights
Patient history is a poor method for identifying children overdue for immunizations. Improved strategies are needed to ensure children receive timely vaccinations and maintain public health.
Area of Science:
- Pediatric Health
- Public Health
- Diagnostic Accuracy
Background:
- Children presenting to healthcare services are routinely assessed for immunization status.
- Accurate assessment of immunization status is crucial for preventing vaccine-preventable diseases.
Purpose of the Study:
- To evaluate the accuracy of using patient history to screen children for their immunization status.
- To determine the sensitivity and specificity of history-taking in identifying children overdue for immunizations.
Main Methods:
- Diagnostic accuracy study comparing patient history with a central immunization database.
- Retrospective review of medical records for children aged 6 months to 6 years.
- Analysis of sensitivity, specificity, and predictive values for detecting overdue immunizations.
Main Results:
- Only 76.3% of children had their immunization history taken.
- Patient history demonstrated low sensitivity (41.3%) but high specificity (98.7%) for detecting overdue immunizations.
- Approximately one in twenty children reported as up-to-date were actually overdue.
Conclusions:
- Relying on patient history alone is insufficient for accurately identifying children overdue for immunizations.
- Alternative strategies, such as electronic health record linkage, are recommended to improve detection rates.
- Enhanced methods are necessary to ensure timely childhood immunizations and protect public health.
Objectives:
Children presenting unplanned to healthcare services are routinely asked about previous immunisations as part of their assessment. We aimed to assess the accuracy of screening children for immunisation status by history.
Design:
Diagnostic accuracy study. We compared information from patient history by a retrospective review of notes and used a central database of child immunisation records as the reference standard.
Setting:
Paediatric emergency department in a tertiary hospital in Oxford, UK.
Participants:
Consecutive children aged 6 months to 6 years presenting over a 2-month period.
Outcome Measures:
Proportion of children with documented immunisation history; sensitivity and specificity of detecting overdue immunisations by history compared to central records.
Results:
1166 notes were surveyed. 76.3% children were asked about immunisations. The proportion of children who were fully immunised on central records was 93.1%. History had a sensitivity of 41.3% (95% CI 27% to 56.8%) and a specificity of 98.7% (95% CI 97.5% to 99.4%) for detecting those who were overdue. Negative predictive value was 95.8% (95% CI 93.9% to 97.2%). Only around a third of children with overdue immunisations are detected by the current screening methods, and approximately 1 in 20 children stated as being up to date are in fact overdue.
Conclusions:
History had poor sensitivity for identifying overdue immunisation. Strategies to improve detection of children overdue with immunisation should focus on alternative strategies for alerting clinicians, such as linkage of community and hospital electronic records.
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