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Updated: May 11, 2026

A 3D Cartographic Description of the Cell by Cryo Soft X-ray Tomography
Published on: March 15, 2021
On the development of three new tools for organizing and sharing information in three-dimensional electron microscopy
Roberto Marabini1, Jose Ramon Macias, Javier Vargas
1Escuela Politécnica Superior, Universidad Autonoma de Madrid, 28049 Madrid, Spain. roberto@cnb.csic.es
Abstract:
Electron microscopy is a valuable tool for elucidating the three-dimensional structures of macromolecular complexes. As the field matures and the number of solved structures increases, the existence of infrastructures that keep this information organized and accessible is crucial. At the same time, standards and clearly described conventions facilitate software maintenance, benefit interoperability with other packages and allow data interchange. This work describes three developments promoting integrative biology, standardization and workflow processing, namely PeppeR, the EMX initiative and Scipion.
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