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[Simultaneous determination of 6 components contained in compound reserpine tablets by Kalman filtering
1Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing.
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|January 1, 1990
Abstract:
Kalman filtering spectrophotometry was investigated to assay the contents of vitamin B1, vitamin B6, chlordiazepoxide, dihydralazine sulfate, promethazine hydrochloride and hydrochlorothiazide in compound reserpine tablets consisting of 10 components. Absorption proportionality constant for each component was obtained by the application of non-negative least square method. The average recoveries for each were 97-103% with CV% less than or equal to 6.9 except vitamin B1 (n = 11).