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Pediatric idiopathic dilated cardiomyopathy: A single center experience

Ahmad S Azhar1

  • 1Department of Pediatric, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Journal of Natural Science, Biology, and Medicine
|May 2, 2013
PubMed

Insights

Pediatric idiopathic dilated cardiomyopathy (IDCM) has high mortality. Younger children with IDCM have better outcomes, with a three-year survival rate of 78% in this study.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Research
  • Clinical Outcomes

Background:

  • Idiopathic dilated cardiomyopathy (IDCM) presents a significant health challenge in children, associated with high mortality rates.
  • Understanding the clinical course and outcomes of pediatric IDCM is crucial for improving patient management.

Purpose of the Study:

  • To retrospectively analyze the clinical characteristics, course, and outcomes of pediatric patients diagnosed with idiopathic dilated cardiomyopathy.
  • To identify factors influencing the prognosis and survival rates in this vulnerable population.

Main Methods:

  • Retrospective review of patient files diagnosed with IDCM at King Abdul Aziz University Hospital, Jeddah, Saudi Arabia (2003-2011).
  • Data collected included medical history, clinical examination, and investigations, categorized by patient outcome.
  • Statistical analysis involved descriptive statistics, chi-square tests, t-tests, Spearman rank correlation, and survival analysis.

Main Results:

  • Eighty-three pediatric patients with IDCM were analyzed, with a female predominance (63.9%).
  • Common presentations included cardiomegaly (86.7%), increased lung vascularity (54%), ECG abnormalities (74%), and left ventricular hypertrophy (74%).
  • The three-year survival rate was 78%, with older age at presentation correlating with poorer outcomes (Spearman's rho = 0.3, P = 0.04).

Conclusions:

  • A majority of pediatric IDCM cases presented within the first year of life.
  • The overall three-year survival rate was 78%, indicating a severe but partially manageable condition.
  • Younger age at presentation was significantly associated with a favorable outcome in pediatric patients with IDCM.
Abstract

Keywords:
Cardiomyopathyechocardiographymortalitysurvival

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