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Related Experiment Video

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Pierre robin sequence.

Noopur Gangopadhyay¹, Derick A Mendonca, Albert S Woo

¹Plastic and Reconstructive Surgery, Washington University School of Medicine, Saint Louis, Missouri.

Seminars in Plastic Surgery

|May 2, 2013

Summary

This summary is machine-generated.

Pierre Robin sequence (PRS) involves micrognathia and glossoptosis causing airway obstruction in infants. Conservative positioning resolves obstruction in most cases, but some require further intervention.

Keywords:

Pierre Robin sequence airway obstruction distraction osteogenesis glossoptosis micrognathia

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Area of Science:

Craniofacial anomalies
Pediatric respiratory distress
Congenital disorders

Background:

Pierre Robin sequence (PRS) is a triad of micrognathia, glossoptosis, and airway obstruction.
It often presents with a hypoplastic mandible, leading to posterior tongue displacement and airway compromise.
PRS is frequently associated with a U-shaped cleft palate and can occur with syndromic diagnoses.

Purpose of the Study:

To review the presentation and management of Pierre Robin sequence.
To outline diagnostic and therapeutic strategies for airway and feeding issues in infants with PRS.
To discuss common surgical interventions for refractory cases.

Main Methods:

Literature review of Pierre Robin sequence.
Clinical assessment of anatomical findings and airway obstruction.
Discussion of conservative and surgical management options.

Main Results:

Conservative positioning resolves airway obstruction in approximately 70% of infants with PRS.
Nasopharyngeal tubes and nasogastric feeding tubes are indicated for persistent desaturation or feeding difficulties.
Surgical options like tongue-lip adhesion and mandibular distraction osteogenesis are considered for non-responsive cases.

Conclusions:

Multidisciplinary evaluation is crucial for infants with PRS to address airway and feeding challenges.
Conservative management is effective for the majority of cases.
Surgical intervention should be considered after ruling out lower airway obstruction and failure of conservative measures.