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Updated: May 11, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(2E)-2-(3-Eth-oxy-2-hy-droxy-benzyl-idene)hydrazinecarboxamide
A Ambili Aravindakshan1, M Sithambaresan, M R Prathapachandra Kurup
1Department of Applied Chemistry, Cochin University of Science and Technology, Kochi 682 022, India.
Abstract:
The title compound, C10H13N3O3, adopts an E conformation with respect to the azomethine bond and crystallizes in the amide form. A classical intra-molecular O-H⋯N hydrogen bond is present. The two N atoms of the hydrazinecarboxamide unit are also involved in inter-molecular N-H⋯O hydrogen bonds, with the O atom of the hydrazinecarboxamide group acting as the acceptor. Pairs of N-H⋯O hydrogen bond link the mol-ecules into centrosymmetric dimers, which are linked by further N-H⋯O hydrogen bonds into chains along the b axis. The chains are linked by C-H⋯π inter-actions.
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