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Updated: May 11, 2026

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

Rarer in a rare.

B Taksande¹, Mm Patil, P Banode

¹Department of Medicine, Jawaharlal Nehru Medical college (DMIMS), Wardha, India.

Annals of Medical and Health Sciences Research

|May 2, 2013

Summary

This summary is machine-generated.

Moyamoya disease, a rare cerebrovascular condition, can present with unusual symptoms like chronic headaches and neuropsychiatric issues, even in young Indian patients. This case highlights less common manifestations of this progressive stenosis disorder.

Keywords:

Headache Moya moya Neuropsychiatry Stroke

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Area of Science:

Neurology
Vascular Neurology
Neuroscience

Background:

Moyamoya disease is a rare, progressive cerebrovascular disorder primarily affecting the internal carotid arteries.
It is characterized by stenosis of the supraclinoid internal carotid arteries and the Circle of Willis.
While more prevalent in Asian populations, its occurrence in India is infrequent.

Observation:

This report details a rare case of Moyamoya disease in a young female presenting with long-standing psychiatric complaints and refractory headaches since childhood.
These symptoms represent atypical initial manifestations of the disease.

Findings:

The patient exhibited rarer neurological and neuropsychiatric symptoms, including chronic headache and psychiatric disturbances.
These findings underscore the diverse clinical spectrum of Moyamoya disease beyond typical stroke events.

Implications:

This case expands the understanding of Moyamoya disease's clinical presentation, emphasizing the need to consider it in patients with unexplained chronic headaches and neuropsychiatric symptoms.
Early recognition of these rarer manifestations is crucial for timely diagnosis and management of Moyamoya disease.
Further research into the varied presentations of Moyamoya disease is warranted to improve diagnostic strategies.