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Updated: May 11, 2026

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Clinicopathological Analysis of miRNA Expression in Breast Cancer Tissues by Using miRNA In Situ Hybridization
Published on: June 7, 2016
A clinico-pathological study on benign breast diseases
Mima B Maychet Sangma1, Kishori Panda, Simon Dasiah
1Assistant Professor, Department of General Surgery.
Summary
Benign breast diseases are common in women, with fibroadenoma being the most frequent diagnosis. A triple assessment method accurately diagnosed breast lumps, reducing patient anxiety about cancer.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Benign breast diseases (BBD) are prevalent in female populations.
- Understanding BBD patterns is crucial for accurate diagnosis and patient management.
- Co-relation of clinical presentation with pathological findings aids in diagnostic accuracy.
Purpose of the Study:
- To investigate the epidemiological patterns of clinically diagnosed benign breast diseases in females.
- To correlate clinical findings with pathological results for improved diagnostic precision.
- To evaluate the accuracy of triple assessment in diagnosing breast conditions.
Main Methods:
- A prospective study of 100 female patients with BBD was conducted.
- Triple assessment (clinical examination, imaging, and biopsy) was employed for early diagnosis.
- Clinical diagnoses were compared with cytological and histological findings for accuracy evaluation.
Main Results:
- Fibroadenoma and breast lumps constituted the highest proportion (48%) of BBD cases.
- Fibrocystic changes (18%) and breast abscesses (12%) were also common findings.
- Rare cases of proliferative disease with atypia and invasive ductal carcinoma were identified, highlighting the importance of accurate diagnosis.
Conclusions:
- Benign breast diseases are common, with fibroadenoma being the most prevalent.
- Triple assessment enables rapid and accurate diagnosis of breast conditions.
- Clinical diagnosis of breast lumps, confirmed by pathology, demonstrated high accuracy (91.95%).
