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CRAO in Moyamoya Disease

Ashok Kumar M1, Amirtha Ganesh B

  • 1Professor, Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute , Puducherry, India .

Journal of Clinical and Diagnostic Research : JCDR
|May 2, 2013
PubMed

Insights

Moyamoya disease (MMD), a rare cerebrovascular condition, can cause central retinal artery occlusion (CRAO). This case report details a young patient with MMD experiencing CRAO, highlighting a rare but significant association.

Area of Science:

  • Neurology
  • Ophthalmology
  • Vascular Medicine

Background:

  • Moyamoya disease (MMD) is a rare, progressive stenosis of intracranial arteries.
  • Cerebrovascular manifestations are common, but ocular complications are exceptionally rare.
  • Central Retinal Artery Occlusion (CRAO) has diverse etiologies, including atherosclerosis, embolism, and vasculitis.

Purpose of the Study:

  • To report a rare case of Central Retinal Artery Occlusion (CRAO) in a young adult.
  • To investigate the association between CRAO and Moyamoya disease (MMD).
  • To highlight the importance of considering MMD in young patients presenting with CRAO.

Main Methods:

  • A case study of a 26-year-old patient presenting with CRAO in the right eye.
  • Cerebral angiography was performed to evaluate intracranial vasculature.
  • Clinical presentation and diagnostic findings were analyzed.

Main Results:

  • The patient was diagnosed with Moyamoya disease (MMD) based on typical cerebral angiography findings.
  • The patient presented with Central Retinal Artery Occlusion (CRAO) in the right eye.
  • This represents a rare co-occurrence of CRAO and MMD.

Conclusions:

  • Moyamoya disease (MMD) can be an underlying cause of Central Retinal Artery Occlusion (CRAO), even in young individuals.
  • Ocular manifestations like CRAO should be considered in the spectrum of Moyamoya disease complications.
  • Further research is warranted to understand the pathophysiology and incidence of CRAO in MMD patients.
Keywords:
Central retinal artery occlusionCerebral angiographyMoya moya disease

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