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Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
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Related Experiment Video

Updated: May 11, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Organic mania in dengue.

Shruti Srivastava1, M S Bhatia, Anurag Jhanjee

  • 1Assistant Professor, Department of Psychiatry, U.C.M.S. & G.T.B. Hospital , Dilshad Garden, Delhi-110095, India .

Journal of Clinical and Diagnostic Research : JCDR
|May 2, 2013
PubMed
Summary

Dengue fever, a significant health issue in Southeast Asia and India, can rarely cause acute psychosis or mania. This case report details a 21-year-old male who developed mania following a Dengue infection.

Keywords:
FeverManiaOrganic ManiaPsychosis

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Published on: July 4, 2007

Area of Science:

  • Neurology
  • Infectious Diseases
  • Psychiatry

Background:

  • Dengue fever is a major public health concern in Southeast Asia, with increasing outbreaks in India.
  • Neurological complications of Dengue, such as encephalitis and encephalopathy, are increasingly reported.
  • A link between Dengue fever and acute psychosis or mania has not been previously documented in medical literature.

Purpose of the Study:

  • To report a rare case of acute mania following Dengue infection.
  • To highlight the potential for Dengue fever to cause psychiatric manifestations.

Main Methods:

  • Case report of a 21-year-old male presenting with symptoms of mania after Dengue infection.
  • Clinical evaluation and diagnosis of Dengue fever and subsequent manic episode.

Main Results:

  • The patient developed classical mania after recovering from Dengue fever.
  • This represents a novel association between Dengue infection and acute manic episode.

Conclusions:

  • Dengue fever may be an underrecognized cause of acute psychosis and mania.
  • Further research is warranted to explore the neurobiological mechanisms linking Dengue virus infection and psychiatric disturbances.