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[Pediatric anesthesia and pharmacokinetics of propofol administered at a constant rate]
B Stimmesse1, F Lassauge, G Clément
1Département d'anesthésie-réanimation, Centre hospitalier universitaire Besançon.
Agressologie: Revue Internationale De Physio-Biologie Et De Pharmacologie Appliquees Aux Effets De L'Agression
|January 1, 1990
Insights
This study examined propofol
Area of Science:
- Anesthesiology and Pharmacology
Abstract:
The pharmacokinetic properties of propofol given at a constant rate, were studied in 10 children. Propofol was administered at a dose according to I.C.I. Pharma advices. For minor surgery, a low quality of general anesthesia was observed in correlation with low plasma levels of propofol. An increase in dosage would be necessary in children above 8 years old.