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Related Concept Videos

Introduction to Hemostasis01:05

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Vascular Spasm01:16

Vascular Spasm

The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last for...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Formation of the Platelet Plug01:22

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...

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Updated: May 11, 2026

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma
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A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

The STOP the Bleeding Campaign.

Rolf Rossaint, Bertil Bouillon, Vladimir Cerny

    Critical Care (London, England)
    |May 3, 2013
    PubMed
    Summary

    Traumatic injuries cause over 5 million deaths annually, with bleeding being a leading preventable cause. The STOP the Bleeding Campaign aims to improve management of traumatic coagulopathy, reducing deaths by 20% in five years.

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    Area of Science:

    • Emergency Medicine
    • Trauma Surgery
    • Hematology

    Background:

    • Traumatic injuries result in over 5 million deaths globally each year.
    • Post-traumatic coagulopathy-induced bleeding is a primary cause of preventable mortality in trauma patients.
    • Insufficient awareness and unclear treatment strategies exacerbate the problem of post-traumatic bleeding.

    Purpose of the Study:

    • To enhance awareness of post-traumatic coagulopathy and its management.
    • To implement European guidelines for managing bleeding trauma patients.
    • To reduce mortality from exsanguination within 24 hours of hospital arrival by at least 20% over five years.

    Main Methods:

    • Publishing European guidelines for bleeding trauma patient management.
    • Promoting and monitoring guideline implementation.
    • Developing educational materials and health quality management tools.

    Main Results:

    • The campaign aims to significantly decrease the number of deaths due to exsanguination.
    • A 20% reduction in mortality within 24 hours is targeted.
    • Improved management protocols for traumatic coagulopathy are a key objective.

    Conclusions:

    • The STOP the Bleeding Campaign addresses a critical gap in trauma care.
    • Effective management of post-traumatic coagulopathy can save lives.
    • Standardized guidelines and increased awareness are crucial for reducing trauma-related deaths.