Related Experiment Video
Updated: May 11, 2026

02:39
Is My Mouse Pregnant? High-Frequency Ultrasound Assessment
Published on: March 18, 2021
[A woman with an umbilical swelling]
René Buijsman1, Niels de Korte
1Kennemer Gasthuis, afd. Algemene Heelkunde, Haarlem, the Netherlands. r.buijsman@westfriesgasthuis.nl
Nederlands Tijdschrift Voor Geneeskunde
|May 3, 2013
Summary
A rare case of transverse colon adenocarcinoma presented as an ulcerative umbilical mass producing feces. The tumor infiltrated the abdominal wall but had no distant metastases, highlighting a complex presentation of gastrointestinal cancer.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Colorectal cancer (CRC) is a significant global health concern.
- Umbilical metastasis (Sister Joseph's nodule) from CRC is uncommon.
- Slime-producing adenocarcinomas represent a specific subtype of CRC.
Observation:
- A 78-year-old female presented with a 9-month history of a painful, ulcerative umbilical swelling.
- The umbilical lesion began to excrete fecal matter, suggesting a gastrocolic fistula.
- Abdominal CT revealed a transverse colon tumor invading the abdominal wall and skin, with no distant metastases.
Findings:
- Histopathological examination of the umbilical mass confirmed a mucinous (slime-producing) adenocarcinoma.
- The tumor's direct invasion and fistula formation presented a rare metastatic pattern.
Implications:
- This case underscores the importance of considering unusual presentations of colorectal cancer.
- Umbilical metastases, though rare, warrant thorough investigation for underlying malignancy.
- Early detection and diagnosis are crucial for managing advanced gastrointestinal cancers.
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