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Percutaneous cholecystostomy is a definitive treatment for acute cholecystitis in elderly high-risk patients
1Department of General Surgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangshu Province, China.
Insights
Percutaneous cholecystostomy (PC) offers a safe and effective treatment for acute cholecystitis (AC) in high-risk elderly patients. This study suggests PC alone is sufficient, obviating the need for subsequent cholecystectomy.
Area of Science:
- Gastroenterology
- Interventional Radiology
- Geriatric Medicine
Background:
- Acute cholecystitis (AC) in elderly, high-risk patients presents treatment challenges.
- Percutaneous cholecystostomy (PC) is an alternative to emergency cholecystectomy with lower risks.
- The necessity of cholecystectomy after PC in this population remains debated.
Purpose of the Study:
- To evaluate the safety and efficacy of percutaneous cholecystostomy (PC) as a definitive treatment for acute cholecystitis (AC) in elderly, high-risk patients.
- To assess the long-term outcomes, including recurrence rates and survival, of AC patients treated solely with PC.
- To determine if cholecystectomy is necessary following successful PC in this specific patient group.
Main Methods:
- Retrospective review of medical records of elderly, high-risk AC patients who underwent PC.
- Analysis of symptom resolution, drainage-related complications, and mortality rates post-PC.
- Evaluation of long-term outcomes including cholecystitis recurrence and patient survival rates.
Main Results:
- PC effectively resolved AC symptoms in 98.6% of patients.
- Drainage-related morbidity and mortality were low (4.1% and 1.4%, respectively).
- No patients required subsequent cholecystectomy; cholecystitis recurrence was 4.1%. One-year and three-year survival rates were 82.2% and 39.7%.
Conclusions:
- Percutaneous cholecystostomy (PC) can be considered a definitive treatment for acute cholecystitis (AC) in elderly, high-risk patients.
- Cholecystectomy is not routinely necessary after successful PC, given the low recurrence rates and limited survival.
- PC offers a safe and effective management strategy, improving outcomes for high-risk AC patients.
Abstract:
Percutaneous cholecystostomy (PC) is an alternative treatment for acute cholecystitis (AC) in elderly patients with high surgical risk and has lower morbidity and mortality than emergency cholecystectomy. There is controversy about whether cholecystectomy should be performed after PC in elderly high-risk patients. Medical records of patients with AC admitted to the Department of Surgery, Jinling Hospital, Nanjing University School of Medicine, China, between January 2004 and July 2009 were reviewed retrospectively. The elderly high-risk patients with AC who underwent PC were selected for further study. The safety, efficacy, and long-term outcome of PC without cholecystectomy were evaluated in these patients. The symptoms of AC resolved in 98.6 per cent of patients; drainage-related morbidity and mortality rates were 4.1 and 1.4 per cent, respectively. No patient underwent cholecystectomy after PC. The recurrence rate of cholecystitis was 4.1 per cent. The one-year survival rate was 82.2 per cent, and the three-year survival rate was 39.7 per cent. No death was related to cholecystitis, but one patient died of septic shock on the second day after PC. Considering limited survival and a low recurrence rate of cholecystitis in elderly high-risk patients with AC, we propose that PC is a definitive treatment and cholecystectomy is not necessary after resolution of AC symptoms.
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