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Diet spanning infancy and toddlerhood is associated with child blood pressure at age 7.5 y
Laima Brazionis1, Rebecca K Golley, Murthy N Mittinty
1Department of Medicine, The University of Melbourne, Melbourne, Australia. laimab@unimelb.edu.au
Insights
Early childhood diet significantly impacts future blood pressure. A less healthy transition diet by age two was linked to higher systolic and diastolic blood pressure at 7.5 years.
Area of Science:
- Pediatric Nutrition
- Cardiovascular Health
- Developmental Pediatrics
Background:
- Early life diet is crucial for long-term health, potentially influencing future blood pressure.
- Limited data exists on the specific impact of early-life dietary patterns on childhood blood pressure.
Purpose of the Study:
- To prospectively examine the association between transition diets in infancy and toddlerhood and blood pressure at age 7.5 years.
- To investigate the role of dietary patterns during the complementary feeding period on later childhood blood pressure.
Main Methods:
- A prospective birth cohort study (Avon Longitudinal Study of Parents and Children) included 1229 children with dietary and blood pressure data.
- Principal components analysis identified two transition dietary patterns.
- Statistical models adjusted for multiple confounders, including maternal and sociodemographic factors, birth variables, breastfeeding, and child body-size metrics.
Main Results:
- A less healthy transition diet pattern was associated with increased systolic blood pressure (0.62 mm Hg/SD) and diastolic blood pressure (0.55 mm Hg/SD) at 7.5 years.
- The association between the less healthy diet score and diastolic blood pressure remained significant after adjusting for height, BMI, and waist circumference.
- The effect of diet on blood pressure was partially mediated by body mass index (BMI).
Conclusions:
- A less healthy diet during the first two years of life is associated with elevated blood pressure in later childhood.
- Body mass index plays a significant role in the relationship between early diet and blood pressure.
- Interventions promoting healthier transition diets may help prevent hypertension later in life.
Background:
Diet in the first 2 y of life may be a pivotal period regarding effects on future blood pressure (BP). However, data on early-life diet and BP in childhood are sparse.
Objective:
We prospectively assessed associations between types of diet spanning infancy and toddlerhood (ie, transition diets across the complementary feeding period) and BP at age 7.5 y.
Design:
In a birth cohort study (Avon Longitudinal Study of Parents and Children; United Kingdom), a total of 1229 children had complete dietary intake data at 6, 15, and 24 mo; BP data at 7.5 y of age; and all 18 covariables.
Results:
Of the 2 transition diets that were extracted by using principal components analysis, the less-healthy diet was associated with an increase in systolic BP of 0.62 mm Hg (95% CI: 0.00, 1.24 mm Hg) and an increase in diastolic BP of 0.55 mm Hg (95% CI: 0.10, 1.00 mm Hg) for every one-unit (SD) increase in the less-healthy-diet score after adjustment for 15 potential confounders, including maternal characteristics and sociodemographic factors, birth variables, and breastfeeding duration. In contrast with systolic BP, the positive association between the less-healthy transition-diet score and diastolic BP persisted after additional adjustment for child body-size factors [height, body mass index (BMI), and waist circumference] at 7.5 y.
Conclusions:
A less-healthy transition diet by age 2 y was associated with higher BP at 7.5 y. The BMI-related reduction in effect size reinforces the importance of BMI on the diet-BP relation.
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