Related Experiment Video

Updated: May 11, 2026

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
09:02

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on: September 27, 2024

Targeting tumors using nanoparticle platforms: a phase I study of a systemically administered gene therapy system

Christopher Larson1, Natalie Mendez, Tony Reid

  • 1Division of Hematology-Oncology, Department of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|May 3, 2013
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors
11:52

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Published on: June 18, 2013

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
08:35

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles

Published on: January 4, 2012

Related Experiment Videos

Last Updated: May 11, 2026

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model
09:02

Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model

Published on: September 27, 2024

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors
11:52

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Published on: June 18, 2013

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles
08:35

Therapeutic Gene Delivery and Transfection in Human Pancreatic Cancer Cells using Epidermal Growth Factor Receptor-targeted Gelatin Nanoparticles

Published on: January 4, 2012

Related Concept Videos

Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Articles linked to this work by shared authors, journal, and citation graph.

CAR expression in invasive breast carcinoma and its effect on adenovirus transduction efficiency.

Breast cancer research : BCR·2024

Lost at SCLC: a review of potential platinum sensitizers.

Cancer metastasis reviews·2024

Hypothesis: AdAPT-001 and pseudoprogression - when seeing is not necessarily believing.

Journal for immunotherapy of cancer·2024

BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors.

Cancer gene therapy·2023

Commentary on oncolytic viruses: past, present, and future.

Journal for immunotherapy of cancer·2023

A Local and Abscopal Effect Observed with Liposomal Encapsulation of Intratumorally Injected Oncolytic Adenoviral Therapy.

Cancers·2023

A complement C5-targeted GalNAc-conjugated siRNA with sustained efficacy in a non-human primate model of IgA nephropathy.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

DC vaccine loaded with Bacteroides fragilis elicits functional cross-reactivity and enhances anti-PD-1 immunotherapy.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

Viral gene replication enhances AAV vector quality and reduces manufacturing costs.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

Unlocking extracellular vesicles-mediated efficient DNA delivery for long-lasting transgene expression.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

The DreAM-plus integrative RNA switch enhances transient AAV expression and reduces side effects of gene editing.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

Human iPSC-derived neural progenitor gene therapy improves outcomes in a neuropathic lysosomal disease.

Molecular therapy : the journal of the American Society of Gene Therapy·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us