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Updated: May 11, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
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Clinically relevant modeling of urodynamics function: the VBN model.

Françoise A Valentini1, Gilbert R Besson, Pierre P Nelson

  • 1ER6-Université Pierre et Marie Curie (Paris 06), Paris, France; Service de Médecine Physique et Réadaptation, Hôpital Rothschild, Paris, France.

Neurourology and Urodynamics
|May 3, 2013
PubMed
Summary
This summary is machine-generated.

The VBN mathematical model aids in understanding lower urinary tract dysfunctions by integrating patient data. Its free software package facilitates broader research into conditions like micturition issues.

Keywords:
mathematical modelmicturitionurodynamics

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Area of Science:

  • Urology
  • Mathematical Modeling
  • Biomedical Engineering

Background:

  • A mathematical model for micturition has been developed over two decades.
  • Published studies cover fundamental aspects and applications in male and female lower urinary tract dysfunctions.
  • A VBN software pack with a Linux version and tutorial is now freely available for wider use.

Purpose of the Study:

  • To describe the VBN mathematical model.
  • To demonstrate the practical utility of the VBN model in clinical and research settings.

Main Methods:

  • The VBN model integrates data from multiple patient recordings, including free uroflowmetry and pressure-flow studies.
  • It allows for coherent patient modeling from data acquired during single or multiple sessions.
  • The model facilitates the analysis of information obtainable from free uroflowmetry.

Main Results:

  • The VBN model enables the prediction of effects from experimental conditions, such as urethral catheters or penile cuffs.
  • It aids in extracting valuable information from free uroflowmetry data.
  • The model's application has led to a deeper understanding of lower urinary tract dysfunctions.

Conclusions:

  • Fitting model computations with real recordings is effective for detecting unexpected phenomena.
  • The VBN model offers a method to enhance the understanding of poorly understood lower urinary tract dysfunctions.
  • Wider adoption of the VBN model is anticipated to advance research in urology.