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Updated: May 11, 2026

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
Published on: March 9, 2021
A heat and moisture mask attenuates cardiovascular stress during cold air exposure
John Seifert1, Megan McNair, Patricia Declercq
1Department of Health and Human Development, Montana State University, Box 173360, 103 Romney Gym, Bozeman, MT 59717, USA.
Background:
Exposure to cold has been shown to cause cardiovascular stress and increased morbidity and mortality. Inhalation of cold, dry air can increase blood pressure and induce myocardial ischemia, particularly in people with preexisting hypertensive cardiovascular disease. Face masks that can warm and humidify inhaled cold air may reduce these cold air pressor effects.
Method:
We compared blood pressure measurements using a heat and moisture exchange mask (HME), a placebo mask (PL), and no mask (NM) in 53 patients with hypertension exposed to a cold chamber environment at -5°C for 1 h. Blood pressure and heart rate were recorded at baseline, and at 15 min intervals from 0 to 60 min of chamber exposure. All patients were taking antihypertensive medications with drug and dosage determined by their own physicians. Data were analyzed by a one-way analysis of variance test with repeated measures, and significant interactions were analyzed by Fisher's least significant differences tests. A post hoc subgroup analysis for the effect of age was performed using Wilcoxon matched-pair rank tests.
Results:
Wearing the HME resulted in significantly lower systolic and mean arterial blood pressures than the PL and NM conditions. Diastolic blood pressures were significantly lower for the HME than the NM, but not the PL condition.
Conclusion:
Subgroup analyses suggested that the effect of the HME in mitigating systolic blood pressure increase from inhalation of cold air was significantly greater for patients aged 60 years or over than for those under 60 years.
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