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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Correlation between baseline echographic features of endophthalmitis, microbiological isolates, and visual outcomes
Aleksandra V Rachitskaya1, Harry W Flynn, Yale L Fisher
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|May 3, 2013
Summary
Advanced echographic features in endophthalmitis, like dense vitreous opacities and retinal detachment, correlate with poorer visual outcomes. No link was found between specific organisms and echographic findings.
Area of Science:
- Ophthalmology
- Medical Imaging
- Infectious Diseases
Background:
- Endophthalmitis diagnosis often relies on clinical presentation.
- Echography plays a crucial role in visualizing intraocular structures in endophthalmitis.
- Understanding echographic features can aid in prognosis.
Purpose of the Study:
- To analyze baseline echographic characteristics in culture-positive and culture-negative endophthalmitis.
- To correlate these echographic findings with final visual acuity outcomes.
Main Methods:
- Retrospective case series of 149 patients with endophthalmitis and baseline echography (1996-2010).
- Echographic features graded: vitreous opacities/membranes, retinal detachment, choroidal detachment.
- Comparison between culture-negative, coagulase-negative staphylococci, and other culture-positive endophthalmitis groups.
Main Results:
- No significant difference in echographic features between culture groups.
- Presence of dense vitreous opacities, marked vitreous membranes, retinal detachment, and choroidal detachment correlated with poorer visual outcomes (P < 0.0001).
Conclusions:
- Echographic features in endophthalmitis are not correlated with the causative organism.
- Advanced echographic findings are significant predictors of worse visual prognosis in endophthalmitis.
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