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Related Experiment Video

Updated: May 11, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

NHS-funded IVF: consequences of NICE implementation.

M Goswami¹, L A Hyslop, A P Murdoch

¹Newcastle Fertility Centre at Life, Reproductive Medicine, International Centre for Life, Times Square, Newcastle upon Tyne NE1 4EP UK. doctormohar@yahoo.co.uk

Human Fertility (Cambridge, England)

|May 4, 2013

Summary

This summary is machine-generated.

Most women under 40 undergoing NHS-funded In Vitro Fertilization (IVF) achieve pregnancy within three cycles. This study shows high cumulative pregnancy rates and timely completion of treatment courses.

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Area of Science:

Reproductive Medicine
In Vitro Fertilization (IVF)
National Health Service (NHS) Funding

Background:

The UK National Institute for Health and Clinical Excellence (NICE) guidelines recommend up to three NHS-funded IVF cycles for subfertile women under 40.
Implementation of these criteria began at The Newcastle Fertility Centre at Life in August 2009.
Evaluating the effectiveness of these funded cycles is crucial for patient outcomes.

Purpose of the Study:

To assess the clinical outcomes of NHS-funded IVF treatments.
To analyze cumulative pregnancy rates following up to three IVF cycles.
To determine the time intervals between successive IVF treatments.

Main Methods:

Retrospective analysis of data from 812 couples starting their first NHS-funded IVF treatment after August 2009.
Data collection continued until 100 couples completed three treatment cycles.
Life table analysis was used to calculate cumulative pregnancy rates; time intervals between treatments were recorded.

Main Results:

Cumulative clinical pregnancy rates per fresh cycle were 30.1% (1st), 50.2% (2nd), and 60.2% (3rd).
Including frozen embryo transfers, cumulative rates increased to 33.5% (1st), 53.4% (2nd), and 62.7% (3rd).
The median time interval between treatments was 10-11 months, with 90.2% of women likely to complete three cycles if needed.

Conclusions:

NICE criteria provide a significant opportunity for subfertile couples to achieve pregnancy through NHS-funded IVF.
The majority of couples utilize the full three-cycle entitlement if necessary.
Completion of the full course of NHS-funded treatment typically occurs within two years.