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Updated: May 11, 2026
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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
Systemic transthyretin amyloidosis in a patient with bent spine syndrome
Kourosh Rezania1, Peter Pytel, Laurel J Smit
1Department of Neurology, The University of Chicago Medical Center, Chicago, IL, USA. krezania@neurology.bsd.uchicago.edu
Abstract:
Wild-type and mutant transthyretin (TTR) are implicated in systemic amyloidosis (ATTR). Myopathy is a rare complication of ATTR amyloidosis, however no patient with bent spine syndrome secondary to ATTR amyloidosis has been reported so far. We present the first case of bent spine syndrome in a patient with wild-type ATTR amyloidosis who also had concomitant Alzheimer's disease.
