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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives01:22

Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives

Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This makes...
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

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Related Experiment Video

Updated: May 11, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Chronic constipation: a critical review.

Guido Basilisco1, Marina Coletta

  • 1Gastroenterology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore, Policlinico, Milan, Italy.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|May 4, 2013
PubMed
Summary

Chronic constipation significantly impacts quality of life and healthcare costs. This review evaluates diagnostic and therapeutic options for adults to improve management and cost-effectiveness.

Keywords:
Clinical reviewConstipationEvidence-based medicine

Related Experiment Videos

Last Updated: May 11, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Area of Science:

  • Gastroenterology
  • Clinical Medicine

Background:

  • Chronic constipation is a prevalent condition with significant effects on patient well-being and healthcare resource utilization.
  • Despite its commonality, there's a lack of cost-effectiveness analyses for diagnostic and therapeutic strategies.
  • Limited long-term comparative data exists for various management approaches.

Purpose of the Study:

  • To critically evaluate current diagnostic and therapeutic options for adult chronic constipation.
  • To identify a rational patient management approach.
  • To clarify controversial aspects for more efficacious and cost-effective clinical management.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) and clinical guidelines.
  • Critical appraisal of evidence for diagnostic accuracy and therapeutic efficacy.
  • Analysis of cost-effectiveness data where available.

Main Results:

  • Evidence supports the efficacy of several older and newer treatments for chronic constipation in well-conducted RCTs.
  • There is ongoing debate regarding the optimal timing for incorporating specific therapies into clinical algorithms.
  • A clear consensus on the most cost-effective diagnostic and treatment pathways is still developing.

Conclusions:

  • A rational approach to managing chronic constipation requires careful consideration of current evidence.
  • Further research is needed to establish cost-effectiveness and long-term outcomes of different strategies.
  • Clinicians need clear guidance to manage chronic constipation effectively and economically.