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Pediatric presentation of splenic marginal zone lymphoma on FDG PET/CT scan
Alireza Rezaee1, Xianfeng Frank Zhao, Vasken Dilsizian
1From the Departments of *Diagnostic Radiology and Nuclear Medicine; and †Pathology, University of Maryland School of Medicine, Baltimore, MD.
Abstract:
Splenic marginal zone lymphoma (SMZL) comprises about 1% of B-cell lymphomas and typically occurs after the age of 50 years. Pediatric SMZL is very rare, and no FDG PET/CT imaging of the disease has been reported. In the current study, a 4-year-old boy with biopsy-proven SMZL had FDG PET/CT for staging, which showed increased metabolic activity in the spleen and left cervical lymph nodes. A second FDG PET/CT for evaluation of treatment response showed complete resolution of abnormal FDG uptake in the nodes and spleen with decrease in size of the nodes.
