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Related Experiment Video

Updated: May 11, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Drug-induced macular edema.

Olga E Makri¹, Ilias Georgalas, Constantine D Georgakopoulos

¹Department of Ophthalmology, Medical School, University of Patras, Rio, 26504 Patras, Greece.

|May 4, 2013

Summary

Macular edema, a cause of vision loss, can be triggered by various systemic and ocular conditions, including diabetes. Certain medications, both oral and ophthalmic, are also identified as potential causes, necessitating careful consideration by clinicians.

Area of Science:

Ophthalmology
Pharmacology

Background:

Macular edema is a significant cause of vision loss, impacting patient quality of life.
It results from various systemic diseases (e.g., diabetes mellitus) and intraocular conditions.
Drug-induced macular edema is an increasingly recognized adverse event.

Purpose of the Study:

To provide an overview of drug-induced macular edema.
To discuss available evidence and pathophysiologic mechanisms.
To propose potential therapeutic strategies.

Main Methods:

Literature review of systemic and ophthalmic medications implicated in macular edema.
Analysis of reported cases and potential pathophysiologic pathways.

Main Results:

Related Experiment Videos

Last Updated: May 11, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Systemic drugs like thiazolidinediones, fingolimod, tamoxifen, taxanes, niacin, and interferons can cause macular edema.
Ophthalmic agents including prostaglandin analogs, epinephrine, timolol, and preservatives are also implicated.
Macular edema is a multifactorial condition with diverse etiologies.

Conclusions:

Drug-induced macular edema is a critical consideration in ophthalmology and other clinical fields.
Understanding the mechanisms is key to managing this condition.
Further research into therapeutic strategies is warranted.