Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

Strain and Elastic Modulus

Strain and Elastic Modulus

The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Differential genioglossus muscle responses to changes in breathing route in awake people with and without obstructive sleep apnea.

Journal of applied physiology (Bethesda, Md. : 1985)·2026

Same author

Mechanical Forces and Mechanotransduction in COPD: Pathogenesis, Clinical Phenotypes, and Therapeutic Implications.

International journal of chronic obstructive pulmonary disease·2026

Same author

Quantitative CT histogram indices for abdominal muscles are associated with coronary artery disease severity.

Clinical radiology·2025

Same author

Global, regional and national burden of asthma attributable to NO<sub>2</sub> from 1990 to 2021: an analysis from the Global Burden of Disease Study 2021.

BMJ open·2025

Same author

Nanoscale LiZnN - Luminescent Half-Heusler Quantum Dots.

ACS applied optical materials·2023

Same author

MiRNA-30a-5p/VCAN Arrests Tumor Metastasis via Modulating the Adhesion of Lung Adenocarcinoma Cells.

Applied biochemistry and biotechnology·2023

Same journal

Reproducibility of Splanchnic Blood Flow Measured Using Phase-Contrast MRI.

NMR in biomedicine·2026

Same journal

Restriction-Weighted Q-Space Trajectory Imaging (ResQ): Toward Mapping Diffusion-Time Effects With Tensor-Valued Diffusion Encoding in Human Prostate Cancer Xenografts.

NMR in biomedicine·2026

Same journal

In Vivo Quantitative Detection of PEGylated Macromolecules by Magnetic Resonance Spectroscopy.

NMR in biomedicine·2026

Same journal

Metabolic Assessment in Human Pluripotent Stem Cell-Derived Cerebral Organoids Using HR-MAS NMR Spectroscopy.

NMR in biomedicine·2026

Same journal

Characterizing Metabolic and Compositional Heterogeneity of Calf Muscle Using CEST MRI at 3 T.

NMR in biomedicine·2026

Same journal

Estimating the Sodium Content: A Case Series of Benign and Malignant Renal Tumours Using <sup>23</sup>Na-MRI at 3 T.

NMR in biomedicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 11, 2026

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Published on: July 20, 2022

Measuring anisotropic muscle stiffness properties using elastography.

M A Green¹, G Geng, E Qin

¹Neuroscience Research Australia, Randwick, NSW, Australia; School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

NMR in Biomedicine

|May 4, 2013

Summary

This summary is machine-generated.

Skeletal muscle mechanical properties show significant anisotropy, with higher shear modulus parallel to muscle fibers. This finding, using MR elastography and DTI, offers insights into muscle health and disease.

Keywords:

MR elastography anisotropy diffusion tensor imaging muscle shear modulus stiffness

More Related Videos

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

Published on: September 3, 2021

Related Experiment Videos

Last Updated: May 11, 2026

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Published on: July 20, 2022

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

Published on: September 3, 2021

Area of Science:

Biomechanics
Musculoskeletal Imaging
Medical Physics

Background:

Anisotropic mechanical properties of skeletal muscle are poorly understood.
In vivo quantification of these properties is limited.
Understanding muscle mechanics is crucial for diagnosing diseases, aging effects, and injuries.

Purpose of the Study:

To measure shear modulus anisotropy in human lower leg skeletal muscles.
To utilize noninvasive MR elastography (MRE) and diffusion tensor imaging (DTI).
To establish baseline anisotropic values for future clinical applications.

Main Methods:

Employed MR elastography (MRE) and diffusion tensor imaging (DTI).
Measured shear modulus parallel (μ‖) and perpendicular (μ⊥) to muscle fiber direction.
Included 10 healthy subjects, focusing on medial gastrocnemius, soleus, and tibialis anterior muscles.

Main Results:

Significant anisotropy observed in all tested muscles (medial gastrocnemius, soleus, tibialis anterior).
Shear modulus parallel to fibers was consistently greater than perpendicular (P < 0.001 for gastrocnemius and soleus, P = 0.03 for tibialis anterior).
No significant differences in anisotropy were found across the studied muscle groups.

Conclusions:

This study provides the first direct estimates of anisotropic shear modulus in the triceps surae muscle group.
The MRE-DTI technique shows promise for assessing mechanical anisotropy changes.
Potential applications include monitoring disease, aging, and injury impacts on muscle function.