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Updated: May 11, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
[Undiagnosed Whipple's disease with a lethal outcome]
Daniel Farkaš1, Marián Svajdler Ml, Silvia Farkašová Iannaccone
1Úrad pre Dahlad nad Zdravatnou Starostlivastou, SlaPA Pracoviska, Kosice. farkas.dany@gmail.com
Abstract:
Whipples disease is a rare multisystem disease caused by rod-shaped bacteria Tropheryma whipplei. Although it affects all age groups, the typical patient is a middle-aged white man. The clinical signs are very heterogeneous and depend on the stage of the disease. The most common is abdominal manifestation characterized by weight loss, disability, chronic diarrhea and abdominal pain. Untreated Whipples disease is almost always fatal. We describe probably the first published case of undiagnosed Whipples disease with a lethal outcome in Slovakia, occuring in a 33-year old white man with involvement of the gastrointestinal tract, abdominal lymphatic nodes and brain, who died of bronchopneumonia.
Insights
Whipples disease, a rare bacterial infection, can be fatal if undiagnosed. This case highlights a lethal outcome in a 33-year-old man with gastrointestinal, lymphatic, and brain involvement.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Neurology
Background:
- Whipples disease is a rare, systemic bacterial infection caused by Tropheryma whipplei.
- It typically affects middle-aged white men, presenting with diverse symptoms.
- Abdominal manifestations like weight loss and diarrhea are common; untreated cases are often fatal.
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