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Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...

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Related Experiment Video

Updated: May 11, 2026

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Treating severe and enduring anorexia nervosa: a randomized controlled trial.

S Touyz1, D Le Grange, H Lacey

  • 1School of Psychology and Centre for Eating and Dieting Disorders (Boden Institute), School of Psychology, University of Sydney, NSW, Australia.

Psychological Medicine
|May 7, 2013
PubMed
Summary

Cognitive Behavioral Therapy (CBT-AN) and Specialist Supportive Clinical Management (SSCM) both improved severe and enduring anorexia nervosa (SE-AN) outcomes. CBT-AN showed greater social adjustment and readiness for recovery at follow-up.

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Last Updated: May 11, 2026

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Eating Disorders Research

Background:

  • Severe and enduring anorexia nervosa (SE-AN) lacks evidence-based treatments.
  • This study addresses the treatment gap for adults with SE-AN.

Purpose of the Study:

  • To evaluate the relative efficacy of cognitive behavioral therapy for anorexia nervosa (CBT-AN) versus specialist supportive clinical management (SSCM) in adults with SE-AN.
  • To compare outcomes including quality of life, mood, and social adjustment.

Main Methods:

  • A multi-site randomized controlled trial (RCT) involving 63 participants with a diagnosis of anorexia nervosa (AN) and at least a 7-year illness history.
  • Participants received 30 outpatient visits of either CBT-AN or SSCM over 8 months.
  • Assessments included quality of life, mood disorder symptoms, social adjustment, weight, eating disorder psychopathology, motivation for change, and healthcare burden at baseline, end of treatment, and 6- and 12-month follow-ups.

Main Results:

  • Both CBT-AN and SSCM groups showed significant improvements at end of treatment (EOT) and follow-up, with no differences at EOT.
  • At 6-month follow-up, CBT-AN demonstrated superior social adjustment (Weissman Social Adjustment Scale).
  • At 12-month follow-up, CBT-AN showed lower Eating Disorder Examination (EDE) global scores and higher readiness for recovery compared to SSCM.

Conclusions:

  • Both CBT-AN and SSCM are acceptable and effective treatments for severe and enduring anorexia nervosa (SE-AN), achieving high retention rates.
  • While both therapies yield improvements, CBT-AN demonstrated specific advantages in social adjustment and recovery motivation at longer-term follow-up.
  • Findings suggest treatment differences align with the distinct therapeutic approaches of CBT-AN and SSCM.