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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Alterations in Respiration II01:30

Alterations in Respiration II

There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Understanding Sleep01:11

Understanding Sleep

Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...

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Related Experiment Video

Updated: May 11, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Sleep-disordered breathing: effects on brain structure and function.

Ronald M Harper1, Rajesh Kumar, Jennifer A Ogren

  • 1Department of Neurobiology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA 90095, USA; Brain Research Institute, University of California at Los Angeles, Los Angeles, CA 90095, USA.

Respiratory Physiology & Neurobiology
|May 7, 2013
PubMed
Summary
This summary is machine-generated.

Sleep-disordered breathing causes central nervous system injury, impacting breathing, mood, memory, and blood pressure. This neural damage, often unilateral, affects autonomic functions and poses risks for heart rhythm.

Keywords:
AutonomicCongenital central hypoventilationDyspneaHypoxiaMagnetic resonance imagingNeural injuryObstructive sleep apnea

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Related Experiment Videos

Last Updated: May 11, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Area of Science:

  • Neurology
  • Respiratory Medicine
  • Cardiology

Background:

  • Sleep-disordered breathing (SDB) is linked to neural injury affecting multiple physiological systems.
  • This injury impacts sensory processing, motor control, and autonomic regulation.
  • Brain regions involved in mood, cognition, and metabolic control are also affected.

Purpose of the Study:

  • To investigate the extent and nature of central nervous system (CNS) injury associated with SDB.
  • To highlight the broad physiological consequences of SDB-induced neural damage.

Main Methods:

  • Review of structural magnetic resonance imaging findings in SDB patients.
  • Analysis of functional distortions in brain activity related to autonomic and respiratory functions.

Main Results:

  • SDB is associated with neural injury in areas controlling chemoreception, respiration, and blood pressure.
  • Cognitive and emotional processing centers, as well as glycemic control structures, show damage.
  • Injury is often unilateral, affecting axonal projections and raising concerns for arrhythmia.
  • Functional imaging reveals distortions in autonomic and breathing control areas.

Conclusions:

  • Sleep-disordered breathing should be recognized as a condition involving significant CNS injury and functional impairment.
  • The unilateral nature of the damage presents unique risks for sympathetic discharge and cardiac arrhythmias.
  • The precise mechanisms driving SDB-related neural injury require further elucidation.