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Published on: August 30, 2018
[100 essential drugs. An internal medicine approach]
M Thomas1, P Arlet, O Aumaitre
1Faculté de médecine de Bobigny, université Paris 13, 74 rue Marcel-Cachin, Bobigny, France. michel.thomas94@wanadoo.fr
A "wise list" of 100 essential medicines was created by French internists to reduce drug misuse and costs. This curated list covers 95% of common disorders, improving healthcare efficiency.
Area of Science:
- Pharmacology
- Public Health
- Clinical Medicine
Background:
- France has over 4600 drugs, leading to potential misuse, increased side effects, and high costs.
- The World Health Organization recommends developed countries create essential drug lists.
- Previous essential drug lists in France had limited impact on clinical practice.
Framework:
- A consensus-driven approach was used to develop a
- wise list
- Ten internists each contributed 100 essential medicines based on experience.
- A final list of 100 essential medicines was validated through expert consensus and internet-facilitated exchanges.
Implementation:
- An initial consensus list of 54 drugs was established, with nine selected by all participants.
- An additional 46 drugs were added to create the final 100-drug list.
- By June 2012, 56 of the listed drugs were available as generics.
Implications:
- The creation of such an essential medicine list is feasible and can optimize drug selection.
- The list provides a foundation for essential medicines in France, covering 95% of common disorders.
- The list will be further refined with input from general practitioners and validated by professional associations.
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