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Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

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Related Experiment Video

Updated: May 11, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

[Practical aspects of medication safety].

Balthasar Hug1

  • 1Klinik für Innere Medizin, Universitätsspital Basel. balthasar.hug@usb.ch

Praxis
|May 7, 2013
PubMed
Summary

Reducing adverse drug events (ADEs) in healthcare is crucial. Implementing electronic prescribing, clinical pharmacists, and identification technologies, alongside workflow analysis, can improve patient safety.

Area of Science:

  • Pharmacovigilance and Patient Safety
  • Health Informatics and Technology Integration

Context:

  • High incidence of adverse drug events (ADEs) in both hospitalized and ambulatory care settings.
  • Significant human suffering, increased healthcare costs, and prolonged hospital stays associated with ADEs.
  • Urgent need for effective strategies to reduce ADE incidence.

Purpose:

  • To outline essential measures for reducing adverse drug events.
  • To emphasize the integration of technological solutions with clinical practice.
  • To highlight the importance of considering health professional workflows in patient safety initiatives.

Summary:

  • Key strategies include electronic prescribing with decision support, clinical pharmacist involvement, therapeutic drug monitoring, smart infusion pumps, and identification technologies (bar-coding, RFID).

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Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices
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Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices

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Related Experiment Videos

Last Updated: May 11, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Safety Precautions and Operating Procedures in an (A)BSL-4 Laboratory: 2. General Practices
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  • Successful implementation requires careful consideration of existing workflows for healthcare professionals.
  • Combining technical tools with scientific analysis is vital for enhancing and maintaining patient safety.

    • Impact:

    • Potential for significant reduction in adverse drug events, mitigating patient harm.
    • Opportunity to decrease healthcare costs and shorten patient lengths of stay.
    • Improved overall patient safety through a holistic approach integrating technology and human factors.