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The cell biology of open and closed mitosis
Barbara Boettcher1, Yves Barral
1Institute of Biochemistry, Department of Biology, Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.
Abstract:
Mitosis is the process of one cell dividing into two daughters, such that each inherits a single and complete copy of the genome of their mother. This is achieved through the equal segregation of the sister chromatids between the daughter cells. However, beyond this simple principle, the partitioning of other cellular components between daughter cells appears to follow a large variety of patterns. We discuss here how the organization of the nuclear envelope during mitosis influences cell division and, subsequently, cellular identity.
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