Related Experiment Video
Updated: May 11, 2026

Half-segmental Diaphyseal Bone Defect Model in Rats for Evaluating Bone Substitute Performance in Load-bearing Regions
Published on: December 30, 2025
Osteogenesis imperfecta and pneumatization of bone-- a hidden reality
Eety Jain1, Ashima Valiathan, Santosh Kumar
1Department of Orthodontics and Dentofacial Orthopedics, Manipal College of Dental Sciences, Manipal, India. dreetyjain@gmail.com
Abstract:
Osteogenesis imperfecta is a bone disorder in which three factors that influence bone strength (quality, mass, and geometry of osseous tissue) are affected. Pneumatization refers to the development of air-filled cavities inside the bone. Knowledge about these air-filled cavities provides valuable information for understanding the diagnosis and spread of various pathologic entities like hemangiomas, giant cell tumors, eosinophilic granulomas, and even metastatic tumor deposits. This paper presents a case in which radiologic, clinical, biochemical, and karyotypic evaluations lead to a diagnosis of osteogenesis imperfecta.
More Related Videos
07:12Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
Published on: September 28, 2017
05:25Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth Movement
Published on: July 21, 2023
Related Concept Videos
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Spongy Bone
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Bone Formation by Endochondral Ossification
Bone Remodeling
Compact Bone
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...