Related Experiment Video

Updated: May 11, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
08:29

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

Published on: February 1, 2019

Interview with Vladimir P Torchilin: liposomal carriers for drug delivery

Vladimir P Torchilin

    Therapeutic Delivery
    |May 8, 2013
    PubMed

    More Related Videos

    Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications08:19

    Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications

    Published on: November 17, 2015

    Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes10:33

    Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

    Published on: July 23, 2016

    Related Concept Videos

    Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

    Site-Targeted Drug Delivery Systems: Polymeric Carriers

    Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
    Bioavailability Enhancement: Drug Permeability Enhancement01:27

    Bioavailability Enhancement: Drug Permeability Enhancement

    After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...
    Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

    Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

    Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
    Drug Delivery: Overview01:16

    Drug Delivery: Overview

    The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
    Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
    Drug Delivery Systems: Different Types01:27

    Drug Delivery Systems: Different Types

    Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
    Modified-Release Drug Delivery Systems: Site-Targeted01:24

    Modified-Release Drug Delivery Systems: Site-Targeted

    Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.