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Related Concept Videos

Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

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Updated: May 11, 2026

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery
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Transcranial color-coded sonography to predict recurrent transient ischaemic attack/stroke.

N Nasr1, G Ssi-Yan-Kai, B Guidolin

  • 1Department of Vascular Neurology, UMR U1048, University of Toulouse, Toulouse, France. nathalie.nasr@orange.fr

European Journal of Neurology
|May 8, 2013
PubMed
Summary

Transcranial color-coded sonography (TCCS) accurately identifies intracranial stenosis in patients with transient ischemic attack (TIA). This imaging technique aids in predicting recurrent TIA or stroke, improving patient triage and management.

Keywords:
arterial occlusionarterial stenosiscerebral circulationmagnetic resonance imagingstroketranscranial color-coded sonographytransient ischaemic attackultrasound/Doppler

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Area of Science:

  • Neurology
  • Medical Imaging
  • Vascular Neurology

Background:

  • Transient Ischemic Attack (TIA) patients at high risk for stroke require accurate identification.
  • Established methods like ABCD(2) score, MRI, and CT angiography aid in risk stratification.
  • The predictive value of Transcranial Color-Coded Sonography (TCCS) in this context remains unevaluated.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of TCCS compared to MRI for intracranial stenosis in TIA patients.
  • To assess the predictive value of TCCS for recurrent TIA or stroke within 7 days.

Main Methods:

  • Retrospective analysis of 159 TIA/minor stroke patients treated within 24 hours.
  • Comparison of TCCS findings with 3D Time-of-Flight MRI for proximal intracranial stenosis (>50%).
  • Calculation of sensitivity, specificity, and predictive values of TCCS for recurrent events.

Main Results:

  • 142 patients (89.3%) had readable TCCS windows; 116 had concurrent TCCS and MRI.
  • Perfect agreement (κ=1) was observed between TCCS and MRI for detecting steno-occlusive lesions.
  • TCCS showed 40% sensitivity and 97.7% specificity for predicting recurrent TIA/stroke, with an adjusted odds ratio of 31.5.

Conclusions:

  • Transcranial Color-Coded Sonography (TCCS) demonstrates high specificity in identifying intracranial stenosis.
  • TCCS can effectively predict recurrent TIA/stroke, aiding in patient triage.
  • This imaging modality offers a valuable tool for managing high-risk TIA patients.