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[Histochemical and electron microscopic observation of the gastric wall after vagotomy]
1Union Hospital, Tongji Medical University, Wuhan.
Abstract:
Eight dogs underwent gastric total truncal vagotomy and another 8 had gastric superselective vagotomy. Specimens were take from anterior wall of gastric corpus and antrum at weeks after operation for histochemical and electron microscopic observation. The results showed: (1) the sympathetic postganglionic fibers in gastric wall were completely damaged. (2) response of gastric antrum mucosa to CCK-8 and gastric G-17 lowered markedly. (3) the amount of parietal cells increased, the structure of follicular atrophied, the number of mitochondrion in cytoplasm, and the stroma and micrailli on folilculi wall increased. (4) The Campylobacter-like organism (CLO) were found in mucosa of gastric antrum and corpus after operation. The authors discussed the role of gastric sympathetic nerve on gastric secretion and movement, and the relationship between CLO and ulcer recurrence after gastric superselective vagotomy.