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The effects and outcomes of electrolyte disturbances and asphyxia on newborns hearing
Chun Liang1, Qi Hong, Tao-Tao Jiang
1Maternal and Child Health Care Hospital of Baoan, Shenzhen 518133, PR China.
Insights
Electrolyte disturbances significantly impair hearing in preterm infants, with hypocalcemia causing lasting hearing issues. Asphyxia did not show a significant effect on newborn hearing screening results.
Area of Science:
- Neonatal care
- Auditory health
- Pediatric neurology
Background:
- Infant hearing is crucial for development.
- Electrolyte disturbances and asphyxia are potential risks to newborn health.
- Understanding their impact on hearing is vital.
Purpose of the Study:
- To investigate the effects of electrolyte disturbances (ED) and asphyxia on infant hearing.
- To evaluate hearing outcomes in newborns screened for these conditions.
Main Methods:
- Large-scale newborn hearing screening (>5000 infants) using transient evoked otoacoustic emission (TEOAE).
- Analysis of hearing pass rates in relation to electrolyte disturbances and asphyxia.
- Follow-up rechecks at 3 months of age.
Main Results:
- Preterm infants with ED showed a significantly reduced TEOAE pass rate (83.1%, P<0.01).
- Full-term infants with ED and infants with asphyxia did not show significant hearing reductions.
- Hypocalcemia significantly lowered the TEOAE pass rate (86.8%, P<0.01), with persistent low pass rates (44.4%) at 3 months.
Conclusions:
- Electrolyte disturbances are a significant risk factor for hearing impairment in preterm infants.
- Hypocalcemia poses a substantial risk, leading to impaired hearing with poor recovery rates.
- Targeted screening and intervention for preterm infants with ED are recommended.
Objective:
To determine the effect of electrolyte disturbances (ED) and asphyxia on infant hearing and hearing outcomes.
Study Design:
We conducted newborn hearing screening with transient evoked otoacoustic emission (TEOAE) test on a large scale (>5000 infants). The effects of ED and asphyxia on infant hearing and hearing outcomes were evaluated.
Result:
The pass rate of TEOAE test was significantly reduced in preterm infants with ED (83.1%, multiple logistic regression analysis: P<0.01) but not in full-term infants with ED (93.6%, P=0.41). However, there was no significant reduction in the pass rate in infants with asphyxia (P=0.85). We further found that hypocalcaemia significantly reduced the pass rate of TEOAE test (86.8%, P<0.01). In the follow-up recheck at 3 months of age, the pass rate remained low (44.4%, P<0.01).
Conclusion:
ED is a high-risk factor for preterm infant hearing. Hypocalcaemia can produce more significant impairment with a low recovery rate.
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