Related Experiment Video
Updated: May 11, 2026

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
Published on: April 5, 2016
Use of methylprednisolone in acute spinal injury
Ahmed M Alkhani1, Abdulsattar H Ghomraoui
1Division of Neurosurgery, Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, MBC - 76, PO Box 3354, Riyadh 11211, Kingdom of Saudi Arabia. Tel. +966 (1) 4647272 Ext. 32772 or 32773. Fax. +966 (1) 4424763.
Objective:
To obtain an appraisal for the use of methylprednisolone (MP) in the early management of acute spinal cord injury (SCI) in our health system and the attitude to its use.
Methods:
A printed questionnaire on MP in acute SCI was distributed to all major spinal and neurosurgical centers in Riyadh, Kingdom of Saudi Arabia between October and November 2001.
Results:
A total of 31 replies were collected for statistical analysis. There were 23 replies from doctors (74%) who see 5 or more cases of acute SCI per year. Sixteen doctors (53%) use MP in acute SCI (National Acute Spinal Cord Injury Studies [NASCIS] protocol) regularly, 11 (37%) use it occasionally and 3 (10%) never use it. The use of MP in acute SCI was suggested as a standard of care by 16%, recommended only by 48% and considered optional by 35%. In addition, a review of the literature on the results of the NASCIS I, II and III was conducted.
Conclusion:
Our results confirm the diversities in clinical practice regarding the use of MP in acute SCI. They also raise the issue of the need for specialized centers in spinal trauma with a unified protocol for treatment throughout the Kingdom.
More Related Videos
04:19Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
11:57Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
Published on: February 23, 2015